Ebi3 Rat Monoclonal Antibody [Clone ID: DNT27]

CAT#: TA320323

Rat Anti-Mouse EBI3 (IL-27 subunit) Purified (25 ug)

Product Images

Mouse IL-27 Recombinant Protein (lane 1) and mouse bone marrow-derived dendritic cells stimulated with LPS (lane 2) or left untreated (lane 3) were analyzed by SDS-PAGE followed by immunoblotting with 5 ug/ml of Anti-Mouse EBI3 (IL-27 subunit) Purified. Bands were visualized with Anti-Rat IgG HRP.

Specifications

Product Data

• Clone Name: DNT27
• Applications: WB
• Recommended Dilution: WB
• Reactivities: Mouse
• Host: Rat
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: Epstein-Barr virus induced gene 3
• Database Link:
  NP_056581
  Entrez Gene 50498 Mouse
  UniProt ID O35228
• Background: The monoclonal antibody DNT27 reacts with mouse Epstein-Barr Virus-induced gene 3 (EBI3). EBI3 is a 34 kDa soluble protein first identified in B cells that is upregulated after Epstein-Barr virus infection. EBI3 can exist as a homodimer and also heterodimerizes with IL-27α (p28, IL-30) to form the cytokine IL-27. IL-27 is produced most abundantly by dendritic cells and macrophages with some recent reports of expression in NKT cells. Recently, a complex of EBI3 and the p35 subunit of IL-12, called IL-35, has been reported to be produced by regulatory T cells.
• Synonyms: IL-27B; IL27B