Ifngr2 Rat Monoclonal Antibody [Clone ID: R4-6A2]

CAT#: TA320357

Rat Anti-Mouse IFN gamma Purified (500 ug)

Specifications

Product Data

• Clone Name: R4-6A2
• Recommended Dilution: Functional Assay
• Reactivities: Mouse
• Host: Rat
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: interferon gamma receptor 2
• Database Link:
  NP_032364
  Entrez Gene 15980 Mouse
• Background: The R4-6A2 antibody reacts with mouse interferon-γ (IFN-γ ), a homodimeric 15-20 kDa cytokine secreted by Th1 cells. The R4-6A2 antibody is a neutralizing antibody. IFN-γ is an ~20 kDa factor produced by activated T, B and NK cells and is an anti-viral and anti-parasitic cytokine. IFN-γ in synergy with other cytokines, such as TNF-α, inhibits proliferation of normal and transformed cells. Immunomodulatory effects of IFN-γ are exerted on a wide range of cell types expressing the high affinity receptors for IFN-γ. Glycosylation of IFN-γ does not affect its biological activity.
• Synonyms: AF-1; IFGR2; IFNGT1