Itga4 Rat Monoclonal Antibody [Clone ID: R1-2]

CAT#: TA320377

Rat Anti-Mouse CD49d (Integrin alpha 4) Purified (50 ug)

Product Images

Staining of mouse splenocytes with Anti-Mouse CD49d PE. Appropriate isotype controls were used (open histogram). Total viable cells were used for analysis.

Specifications

Product Data

• Clone Name: R1-2
• Applications: FC
• Recommended Dilution: Flow, IHC, Functional Assay, IP
• Reactivities: Mouse
• Host: Rat
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: integrin alpha 4
• Database Link:
  NP_034706
  Entrez Gene 16401 Mouse
  UniProt ID Q00651
• Background: The R1-2 monoclonal antibody reacts with mouse CD49d, the 150 kDa integrin alpha4 subunit. The complex of CD49d non-covalently associated with integrin beta1 (CD29), also known as VLA-4, is a receptor for fibronectin and VCAM-1 (CD106). This complex is expressed by thymocytes, peripheral lymphocytes, monocytes and eosinophils. CD49d also associates with integrin b7 and binds to the Mucosal vascular Addressin (MAdCAM-1).
• Synonyms: CD49D; IA4; MGC90518; VLA-4