Pdcd1 Rat Monoclonal Antibody [Clone ID: RMP1-30]
Other products for "Pdcd1"
Specifications
Product Data | |
Clone Name | RMP1-30 |
Applications | FC |
Recommended Dilution | Flow |
Reactivities | Mouse |
Host | Rat |
Clonality | Monoclonal |
Formulation | Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer |
Concentration | lot specific |
Purification | Affinity purified |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | programmed cell death 1 |
Database Link | |
Background | The RMP1-30 antibody reacts with mouse PD-1 (programmed death-1), a 55 kDa member of the Ig superfamily. PD-1 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) and plays a key role in peripheral tolerance and autoimmune disease in mice. PD-1 is expressed mainly on activated T and B lymphocytes. Two novel B7 Family members have been identified as PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. RMP1??0 does not block the binding of either B7-H1-Ig or B7-DC-Ig to PD-1 transfectants. |
Synonyms | CD279; hPD-1; hPD-l; PD1; SLEB2 |
Reference Data |
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