Pdgfrb Rat Monoclonal Antibody [Clone ID: APB5]

CAT#: TA320443

Rat Anti-Mouse CD140b (PDGF Receptor b) Purified (100 ug)

Product Images

Staining of NIH/3T3 cell line with 0.5 ug of Rat IgG2a kappa Isotype Control Purified (open histogram) or 0.5 ug of Anti-Mouse CD140b (PDGF Receptor b) Purified (filled histogram) followed by Anti-Rat IgG Biotin and Streptavidin PE. Total viable cells were used for analysis.

Specifications

Product Data

• Clone Name: APB5
• Applications: FC
• Recommended Dilution: Flow, IHC, WB
• Reactivities: Mouse
• Host: Rat
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: platelet derived growth factor receptor, beta polypeptide
• Database Link:
  NP_032835
  Entrez Gene 18596 Mouse
  UniProt ID P05622
• Background: The APB5 monoclonal antibody reacts with the mouse CD140b molecule, the β chain of the platelet derived growth factor receptor (PDGF receptor). PDGFRb is a receptor tyrosine kinase that forms dimers on the surface upon ligand binding and phosphorylates substrates. Dimers of PDGFR consist of either homodimers of α/α, β/β, or heterodimers of α/β and serve as a substrate for its kinase activity. CD140b is expressed by embryonic tissues and mesenchymal-derived cells of the adult mouse tissues. The PDGFR β chain is reported to play a significant role in formation of fibrous atherosclerotic lesions.
• Synonyms: CD140b; JTK12; PDGF-R-beta; PDGFR; PDGFR1