Semaphorin 4D (SEMA4D) Mouse Monoclonal Antibody [Clone ID: eBio133-1C6 (133-1C6)]

CAT#: TA320461

Mouse Anti-Human CD100 (SEMA4D) Purified (25 ug)

Product Images

Staining of normal human peripheral blood cells with 0.25 ug of Mouse IgM Isotype Control Purified, (open histogram) or Anti-Human CD100 (SEMA4D) Purified (filled histogram) followed by Anti-Mouse IgM PE. Cells in the lymphocyte gate were used for analysis.

Specifications

Product Data

• Clone Name: eBio133-1C6 (133-1C6)
• Applications: FC
• Recommended Dilution: Flow, ELISA, IP
• Reactivities: Human
• Host: Mouse
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: semaphorin 4D
• Database Link:
  NP_872441
  Entrez Gene 349236 Entrez Gene 10507 Human
  UniProt ID Q92854
• Background: The eBio133-1C6 monoclonal antibody reacts with human CD100, a member of the class IV semaphorin family also called sema4D. CD100 promotes angiogenesis, invasive growth, proliferation, and anti-apoptosis of cancer cells in vitro. Furthermore CD100 is a costimulatory molecule in adaptive immune responses by switching off negative signalling from CD72. In addition to CD72 another ligand is Plexin-B1. It has been shown that higher expression levels of CD100 are correlated with poor survival in soft tissue sarcoma patients. Expression is found in both hematopoietic and non-hematopoietic cells.CD100 is expressed on resting T cells and NK cells and B cell. CD100 can also exist as a soluble form.
• Synonyms: FLJ39737