Tnfsf10 Rat Monoclonal Antibody [Clone ID: N2B2]

CAT#: TA320500

Rat Anti-Mouse CD253 (TRAIL) Purified (50 ug)

Product Images

Staining of mouse TRAIL-transfected cells with 0.5 ug of Rat IgG2a kappa Isotype Control Purified (open histogram) or 0.25 ug of Anti-Mouse CD253 (TRAIL) Purified (filled histogram) followed by F (ab')2 Anti-Rat IgG PE. Total viable cells were used for analysis.

Specifications

Product Data

• Clone Name: N2B2
• Applications: FC
• Recommended Dilution: Flow, Functional Assay, IP
• Reactivities: Mouse
• Host: Rat
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: tumor necrosis factor (ligand) superfamily, member 10
• Database Link:
  NP_033451
  Entrez Gene 22035 Mouse
  UniProt ID P50592
• Background: The N2B2 monoclonal antibody reacts with mouse TNF-related apoptosis-inducing ligand (TRAIL), a member of the TNF superfamily. TRAIL is not detected on the surface of freshly isolated T, B, or NK cells, but can be induced preferentially on CD3- NK1.1+ NK cells after stimulation with IL-2 or IL-15. N2B2 inhibits IL-2- or IL-15-activated NK cell cytotoxicity against mouse fibrosarcoma L929 target cells.
• Synonyms: Apo-2L; APO2L; CD253; TL2; TRAIL