Adenylate Kinase 1 (AK1) Rabbit Polyclonal Antibody

CAT#: TA321144

Anti-AK1 Rabbit Polyclonal Antibody

Product Images

Gel: 10%SDS-PAGE Lysate: 40 μg Lane: Human fetal muscle tissue Primary antibody: TA321144 (AK1 Antibody) at dilution 1/200 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 10 seconds

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Human fetal muscle tissue
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 1-194 amino acids of Human Adenylate kinase isoenzyme 1
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 22 kDa
• Gene Name: adenylate kinase 1
• Database Link:
  NP_000467
  Entrez Gene 11636 MouseEntrez Gene 24183 RatEntrez Gene 203 Human
  UniProt ID P00568
• Background: Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates; adenylate isozyme 1 (AK1); 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle; brain and erythrocytes; whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.
• Synonyms: HTL-S-58j

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Purine metabolism