IL10RB Rabbit Polyclonal Antibody
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Other products for "IL10RB"
Specifications
Product Data | |
Applications | ELISA, IHC |
Recommended Dilution | IHC: 25-100 Positive control: Human cervical cancer Predicted cell location: Cytoplasm, Cell membrane |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Fusion protein corresponding to a region derived from 19-225 amino acids of Human Interleukin-10 receptor subunit beta |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | interleukin 10 receptor subunit beta |
Database Link | |
Background | The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes; IFAR2; IFNAR1; and IFNGR2; form a class II cytokine receptor gene cluster located in a small region on chromosome 21. |
Synonyms | CDW210B; CRF2-4; CRFB4; D21S58; D21S66; IL-10R2 |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway |
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