beta 2 Microglobulin (B2M) Rabbit Polyclonal Antibody
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Specifications
| Product Data | |
| Applications | ELISA, WB |
| Recommended Dilution | WB: 200-1000 WB positive control: Raji cells and human thyroid cancer tissue |
| Reactivities | Human, Mouse, Rat |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Full length fusion protein |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Predicted Protein Size | 14 kDa |
| Gene Name | beta-2-microglobulin |
| Database Link | |
| Background | This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia. |
| Synonyms | IMD43 |
| Reference Data | |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | Antigen processing and presentation |
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