APJ Receptor (APLNR) Rabbit Polyclonal Antibody

CAT#: TA321681

Anti-APLNR Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: OP9 cells
  IHC: 15-50
  Positive control: Human brain
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 272-380 amino acids of human apelin receptor
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 43 kDa
• Gene Name: apelin receptor
• Database Link:
  NP_005152
  Entrez Gene 23796 MouseEntrez Gene 83518 RatEntrez Gene 187 Human
  UniProt ID P35414
• Background: This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor; but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems; in glucose metabolism; in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified.?
• Synonyms: AGTRL1; APJ; APJR; HG11

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction