p23 (PTGES3) Rabbit Polyclonal Antibody

CAT#: TA321771

Anti-PTGES3 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: ELISA, IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human colon cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Full length fusion protein
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: prostaglandin E synthase 3
• Database Link:
  NP_006592
  Entrez Gene 56351 MouseEntrez Gene 362809 RatEntrez Gene 10728 Human
  UniProt ID Q15185
• Background: Prostaglandin E synthase 3 (cytosolic)?is an?enzyme?that in humans is encoded by the PTGES3?gene. The protein encoded by this gene is also known as p23 which functions as a chaperone which is required for proper functioning of the glucocorticoid and other steroid receptors. Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation; by promoting disassembly of transcriptional regulatory complexes.
• Synonyms: cPGES; P23; TEBP

Reference Data

• Protein Families: Druggable Genome, Nuclear Hormone Receptor