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Dysbindin (DTNBP1) Rabbit Polyclonal Antibody
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Specifications
| Product Data | |
| Applications | IHC |
| Recommended Dilution | IHC: 20-100 Positive control: Human brain Predicted cell location: Cytoplasm |
| Reactivities | Human, Mouse, Rat |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 347-351 amino acids of Human dystrobrevin binding protein 1 |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Gene Name | dystrobrevin binding protein 1 |
| Database Link | |
| Background | This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes; platelet dense granules; and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1); and binds to alpha- and beta-dystrobrevins; which are components of the dystrophin-associated protein complex (DPC). Mutations in this gene are associated with Hermansky-Pudlak syndrome type 7. This gene may also be associated with schizophrenia. Multiple transcript variants encoding distinct isoforms have been identified for this gene. |
| Synonyms | BLOC1S8; DBND; HPS7; My031; SDY |
| Reference Data | |
| Protein Families | Druggable Genome |
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