RHOC Rabbit Polyclonal Antibody

CAT#: TA321942

Anti-RHOC Rabbit Polyclonal Antibody

Product Images

Gel: 12%SDS-PAGE Lysate: 40 μg Lane: Human fetal brain tissue Primary antibody: TA321942 (RHOC Antibody) at dilution 1/300 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 2 minutes

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Human fetal brain tissue
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 179-189 amino acids of Human ras homolog family member C
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 22 kDa
• Gene Name: ras homolog family member C
• Database Link:
  NP_786886
  Entrez Gene 11853 MouseEntrez Gene 295342 RatEntrez Gene 389 Human
  UniProt ID P08134
• Background: This gene encodes a member of the Rho family of small GTPases; which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape; attachment; and motility. The protein encoded by this gene is prenylated at its C-terminus; and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants; encoding the same protein; have been identified.
• Synonyms: ARH9; ARHC; H9; RHOH9

Reference Data

• Protein Families: Druggable Genome