EDG8 (S1PR5) Rabbit Polyclonal Antibody

CAT#: TA322167

Anti-S1PR5 Rabbit Polyclonal Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane: Human fetal brain tissue lysate Primary antibody: TA322167 (S1PR5 Antibody) at dilution 1/200 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 30 seconds

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC: 50-100
  Positive control: Human esophagus cancer
  Predicted cell location: Cell membrane
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 25-39 amino acids of human sphingosine-1-phosphate receptor 5
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 42 kDa
• Gene Name: sphingosine-1-phosphate receptor 5
• Database Link:
  NP_110387
  Entrez Gene 60399 RatEntrez Gene 94226 MouseEntrez Gene 53637 Human
  UniProt ID Q9H228
• Background: The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation; apoptosis; motility; and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors are S1P receptors; others are LPA receptors.
• Synonyms: Edg-8; EDG8; S1P5; SPPR-1; SPPR-2

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction