CBX8 Rabbit Polyclonal Antibody
Other products for "CBX8"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | WB: 500-2000 WB positive control: 293T and 231 cell lysates IHC: 50-200 Positive control: Human cervical cancer Predicted cell location: Nucleus |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Fusion protein corresponding to a C terminal 300 amino acids of human chromobox homolog 8 |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 43 kDa |
Gene Name | chromobox 8 |
Database Link | |
Background | Chromobox protein homolog 8 is a protein that in humans is encoded by the CBX8 gene.CBX8 has been shown to interact with RING1 and MLLT1.Component of a Polycomb group (PcG) multiprotein PRC1-like complex; a complex class required to maintain the transcriptionally repressive state of many genes; including Hox genes; throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119'; rendering chromatin heritably changed in its expressibility. |
Synonyms | PC3; RC1 |
Reference Data | |
Protein Families | Transcription Factors |
Documents
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