DAP13 (NDUFA12) Rabbit Polyclonal Antibody

CAT#: TA322288

Anti-NDUFA12 Rabbit Polyclonal Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human brain tissue using TA322288 (NDUFA12 Antibody) at dilution 1/50 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA322288 (NDUFA12 Antibody) at dilution 1/50, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human brain
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 40-53 amino acids of Human NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: NADH:ubiquinone oxidoreductase subunit A12
• Database Link:
  NP_061326
  Entrez Gene 66414 MouseEntrez Gene 299739 RatEntrez Gene 55967 Human
  UniProt ID Q9UI09
• Background: This gene encodes a protein which is part of mitochondrial complex 1; part of the oxidative phosphorylation system in mitochondria. Complex 1 transfers electrons to ubiquinone from NADH which establishes a proton gradient for the generation of ATP. Mutations in this gene are associated with Leigh syndrome due to mitochondrial complex 1 deficiency. Pseudogenes of this gene are located on chromosomes 5 and 13. Alternative splicing results in multiple transcript variants.
• Synonyms: B17.2; DAP13