ADAMTS2 Rabbit Polyclonal Antibody

CAT#: TA322388

Anti-ADAMTS2 Rabbit Polyclonal Antibody

Product Images

Predicted cell location: Secreted, Extracellular space, Extracellular matrix. Positive control: Human colon and gastric cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human colon cancer tissue using ADAMTS2 antibody at dilution 1/25, on the right is treated with the synthetic peptide. (Original magnification:x 200)

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  Predicted cell location: Secreted, Extracellular space, Extracellular matrix. Positive control: Human colon and gastric cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human gastric cancer tissue using ADAMTS2 antibody at dilution 1/25, on the right is treated with the synthetic peptide. (Original magnification:x200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: ELISA: 1:2000-5000, IHC: 1:25-100
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 1198-1211 amino acids of human ADAM metallopeptidase with thrombospondin type 1 motif, 2
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: ADAM metallopeptidase with thrombospondin type 1 motif 2
• Database Link:
  NP_055059
  Entrez Gene 216725 MouseEntrez Gene 287899 RatEntrez Gene 9509 Human
  UniProt ID O95450
• Background: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules; including a propeptide region; a metalloproteinase domain; a disintegrin-like domain; and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs; and some have unique C-terminal domains. The enzyme encoded by this gene excises the N-propeptide of type I; type II and type V procollagens. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC; a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants.
• Synonyms: ADAM-TS2; ADAMTS-2; ADAMTS-3; NPI; PC I-NP; PCI-NP; PCINP; PCPNI; PNPI

Reference Data

• Protein Families: Druggable Genome