MAP4K5 Rabbit Polyclonal Antibody

CAT#: TA322481

Anti-MAP4K5 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: ELISA, IHC
• Recommended Dilution: IHC: 15-50
  Positive control: Human ovarian cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 506-819 amino acids of human mitogen-activated protein kinase kinase kinase kinase?
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: mitogen-activated protein kinase kinase kinase kinase 5
• Database Link:
  NP_006566
  Entrez Gene 399510 MouseEntrez Gene 503027 RatEntrez Gene 11183 Human
  UniProt ID Q9Y4K4
• Background: This gene encodes a member of the serine/threonine protein kinase family; that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells; which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.?
• Synonyms: GCKR; KHS; KHS1; MAPKKKK5

Reference Data

• Protein Families: Druggable Genome, Protein Kinase