NCoR (NCOR1) Rabbit Polyclonal Antibody
Other products for "NCOR1"
Specifications
Product Data | |
Applications | IHC |
Recommended Dilution | IHC: 100-300 Positive control: Human cervical cancer Predicted cell location: Cytoplasm, Nucleus |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide corresponding to a region derived from 840-894 amino acids of Human nuclear receptor corepressor 1 |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | nuclear receptor corepressor 1 |
Database Link | |
Background | This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20. |
Synonyms | hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1 |
Reference Data | |
Protein Families | Druggable Genome |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.