Neurofilament (NEFL) Rabbit Polyclonal Antibody

CAT#: TA322530

Anti-NEFL Rabbit Polyclonal Antibody


USD 345.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Applications ELISA, IHC
Recommended Dilution IHC: 25-100
Positive control: Human colon cancer
Predicted cell location: Cell membrane
Reactivities Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Full length fusion protein
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name neurofilament, light polypeptide
Background Neurofilaments are type IV intermediate filament heteropolymers composed of light; medium; and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E); disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.
Synonyms CMT1F; CMT2E; NF-L; NF68; NFL; PPP1R110
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS
Protein Pathways Amyotrophic lateral sclerosis (ALS)

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