IL18R Beta (IL18RAP) Rabbit Polyclonal Antibody

CAT#: TA322813

Anti-IL18RAP Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: RAW264.7 cells
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 378-599 amino acids of human interleukin 18 receptor accessory protein
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 68 kDa
• Gene Name: interleukin 18 receptor accessory protein
• Database Link:
  NP_003844
  Entrez Gene 16174 MouseEntrez Gene 373540 RatEntrez Gene 8807 Human
  UniProt ID O95256
• Background: Interleukin 18 receptor accessory protein; also known as?IL18RAP?and?CDw218b?(cluster of differentiationw218b); is a human?gene. The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP); a ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and this protein is required for the activation of NF-?B and MAPK8 (JNK) in response to IL18.
• Synonyms: ACPL; CD218b; CDw218b; IL-1R-7; IL-1R7; IL-1RAcPL; IL-18R-beta; IL-18RAcP; IL-18Rbeta; IL18RB

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction