IL18R Beta (IL18RAP) Rabbit Polyclonal Antibody

CAT#: TA322813

Anti-IL18RAP Rabbit Polyclonal Antibody


USD 345.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Applications ELISA, WB
Recommended Dilution WB: 500-2000
WB positive control: RAW264.7 cells
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein corresponding to a region derived from 378-599 amino acids of human interleukin 18 receptor accessory protein
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 68 kDa
Gene Name interleukin 18 receptor accessory protein
Background Interleukin 18 receptor accessory protein; also known as?IL18RAP?and?CDw218b?(cluster of differentiationw218b); is a human?gene. The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP); a ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and this protein is required for the activation of NF-?B and MAPK8 (JNK) in response to IL18.
Synonyms ACPL; CD218b; CDw218b; IL-1R-7; IL-1R7; IL-1RAcPL; IL-18R-beta; IL-18RAcP; IL-18Rbeta; IL18RB
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction

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