alpha Adducin (ADD1) Rabbit Polyclonal Antibody

CAT#: TA323224

Anti-ADD1 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: ELISA, IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human lung cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Full length fusion protein
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: adducin 1
• Database Link:
  NP_001110
  Entrez Gene 11518 MouseEntrez Gene 24170 RatEntrez Gene 118 Human
  UniProt ID P35611
• Background: Adducins are a family of cytoskeleton proteins encoded by three genes (alpha; beta; gamma). Adducin is a heterodimeric protein that consists of related subunits; which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive; hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast; beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however; not all variants have been fully described.
• Synonyms: ADDA

Reference Data

• Protein Families: Druggable Genome