Acrosin (ACR) Rabbit Polyclonal Antibody

CAT#: TA323227

Anti-ACR Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Human breast cancer tissue lysate
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 407-421 amino acids of human acrosin
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 46 kDa
• Gene Name: acrosin
• Database Link:
  NP_001088
  Entrez Gene 11434 MouseEntrez Gene 24163 RatEntrez Gene 49 Human
  UniProt ID P10323
• Background: Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form; proacrosin. The active enzyme functions in the lysis of the zona pellucida; thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids.
• Synonyms: acrosin; preproacrosin; proacrosin

Reference Data

• Protein Families: Druggable Genome, Protease