ABCE1 Rabbit Polyclonal Antibody

CAT#: TA323290

Anti-ABCE1 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: NIH/3T3 and SKOV3 cells, human ovarian cancer tissue
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 345-562 amino acids of human ATP-binding cassette, sub-family E (OABP), member 1
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 67 kDa
• Gene Name: ATP binding cassette subfamily E member 1
• Database Link:
  NP_001035809
  Entrez Gene 24015 MouseEntrez Gene 361390 RatEntrez Gene 6059 Human
  UniProt ID P61221
• Background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1; MDR/TAP; MRP; ALD; OABP; GCN20; White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor; this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system; the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene.
• Synonyms: ABC38; OABP; RLI; RNASEL1; RNASELI; RNS4I

Reference Data

• Protein Families: Druggable Genome