EP2 (PTGER2) Rabbit Polyclonal Antibody

CAT#: TA323518

Anti-PTGER2 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 500-2000
  WB positive control: A549 cells
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 1-13 amino acids of Human prostaglandin E receptor 2 (subtype EP2), 53kDa
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 40 kDa
• Gene Name: prostaglandin E receptor 2
• Database Link:
  NP_000947
  Entrez Gene 19217 MouseEntrez Gene 81752 RatEntrez Gene 5732 Human
  UniProt ID P43116
• Background: This gene encodes a receptor for prostaglandin E2; a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma. Prostaglandin E2 receptor?(53kDa); also known as?EP2; is a?prostaglandin receptor?for?prostaglandin E2. It is encoded by the human?gene?PTGER2. Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle.
• Synonyms: EP2

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction