Tyrosine Hydroxylase (TH) Rabbit Polyclonal Antibody

CAT#: TA323692

Anti-TH(Phospho-Ser40) Rabbit Polyclonal Antibody

Product Images

Predicted cell location: Cytoplasm. Positive control: Hela cells. Recommended dilution: 1/ 100-200.The image is immunofluorescence of methanol-fixed Hela cells using TH (Phospho-Ser40) antibody at dilution 1/100. (Original magnification:×200)

Specifications

Product Data

• Applications: IF
• Recommended Dilution: ELISA: IF
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide sequence around phosphorylation site of serine 40 (R-Q-S(p)-L-I) derived from Human Tyrosine Hydroxylase (TH).
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: tyrosine hydroxylase
• Database Link:
  NP_000351
  Entrez Gene 21823 MouseEntrez Gene 25085 RatEntrez Gene 7054 Human
  UniProt ID P07101
• Background: The protein encoded by Tyrosine Hydroxylase is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
• Synonyms: DYT5b; DYT14; TYH

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Parkinson's disease, Tyrosine metabolism