Polycystin 2 (PKD2) Rabbit Polyclonal Antibody

CAT#: TA323703

Anti-PKD2 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human ovarian cancer
  Predicted cell location: Cytoplasm, Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 956-968 amino acids of Human polycystic kidney disease 2 (autosomal dominant)
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: polycystin 2, transient receptor potential cation channel
• Database Link:
  NP_000288
  Entrez Gene 18764 MouseEntrez Gene 498328 RatEntrez Gene 5311 Human
  UniProt ID Q13563
• Background: This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel; and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1; and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2.
• Synonyms: APKD2; Pc-2; PC2; PKD4; TRPP2

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane