AGBL3 Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | ELISA, IHC |
Recommended Dilution | IHC: 25-100 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Fusion protein corresponding to C terminal 250 amino acids of human ATP/GTP binding protein-like 3 |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | ATP/GTP binding protein-like 3 |
Database Link | |
Background | CCP3 (cytosolic carboxypeptidase 3), also known as AGBL3 (ATP/GTP-binding protein-like 3), is a 1,001 amino acid cytosolic protein that exists as four alternatively spliced isoforms and belongs to the peptidase M14 family. As a metallocarboxypeptidase, CCP3 binds one zinc ion per subunit and may play a role in the processing of tubulin. The gene that encodes CCP3 consists of approximately 161,457 bases and maps to human chromosome 7q33. Housing over 1,000 genes, chromosome 7 comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. |
Synonyms | CCP3 |
Reference Data |
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