Lactate Dehydrogenase B (LDHB) Rabbit Polyclonal Antibody

CAT#: TA324032

Anti-LDHB Rabbit Polyclonal Antibody

Product Images

Predicted band size: 37 kDa. Positive control: Hela cell lysate. Recommended dilution: 1/ 1000-5000. (Gel: 10%SDS-PAGE Lysate: 30 ug Primary antibody: 1/1000 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:2000-10000, WB: 1:1000-5000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide (KLH-coupled) derived from human LDHB
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 37 kDa
• Gene Name: lactate dehydrogenase B
• Database Link:
  NP_001167568
  Entrez Gene 16832 MouseEntrez Gene 24534 RatEntrez Gene 3945 Human
  UniProt ID P07195
• Background: This gene encodes an enzyme which catalyzes the reversible conversion of lactate and pyruvate, and NAD and NADH, in the glycolytic pathway. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on the X chromosome and on chromosome. Multiple alternatively spliced variants, encoding the same protein, have been identified. Rare LDHB variants result in deficiency of lactate dehydrogenase, a condition with no deleterious effects on health. LDHB deficiency is of interest to laboratory medicine mainly because it can cause misdiagnosis in those disorders in which elevation of serum LDH is expected. Lactate dehydrogenase deficiency can probably be considered a non-disease.
• Synonyms: HEL-S-281; LDH-B; LDH-H; LDHBD; TRG-5

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Cysteine and methionine metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Propanoate metabolism, Pyruvate metabolism