ITGB3BP Rabbit Polyclonal Antibody

CAT#: TA324155

Anti-ITGB3BP Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: IHC: 50-200
  Positive control: Human gasrtic cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Full length fusion protein
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 15 kDa
• Gene Name: integrin subunit beta 3 binding protein
• Database Link:
  NP_001193668
  Entrez Gene 67733 MouseEntrez Gene 362548 RatEntrez Gene 23421 Human
  UniProt ID Q13352
• Background: This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families; thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.
• Synonyms: CENP-R; CENPR; HSU37139; NRIF3; TAP20

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency, Transcription Factors