CBL Rabbit Polyclonal Antibody

CAT#: TA325304

Rabbit Polyclonal CBL (Tyr674) Antibody (Phospho-specific)

Product Images

Western blot analysis of CBL phosphorylation expression in Na2VO3 treated HepG2 whole cell lysates, The lane on the left is treated with the antigen-specific peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000; IHC: 1:50-1:200
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against A synthesized peptide derived from human CBL around the phosphorylation site of Tyrosine 674
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 120 kDa
• Gene Name: Cbl proto-oncogene
• Database Link:
  NP_005179
  Entrez Gene 12402 MouseEntrez Gene 500985 RatEntrez Gene 867 Human
  UniProt ID P22681
• Background: Cbl an adapter protein that functions as a negative regulator of many signaling pathways that start from receptors at the cell surface.
• Synonyms: C-CBL; CBL2; FRA11B; NSLL; RNF55

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Chronic myeloid leukemia, Endocytosis, ErbB signaling pathway, Insulin signaling pathway, Jak-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Ubiquitin mediated proteolysis