Cyclin D3 (CCND3) Rabbit Polyclonal Antibody

CAT#: TA325313

Rabbit Polyclonal Cyclin D3 (Thr283) Antibody (Phospho-specific)

Product Images

Western blot analysis of Cyclin D3 phosphorylation expression in UV treated K562 whole cell lysates, The lane on the left is treated with the antigen-specific peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000; IHC: 1:50-1:200
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against A synthesized peptide derived from human Cyclin D3 around the phosphorylation site of Threonine 283
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 31 kDa
• Gene Name: cyclin D3
• Database Link:
  NP_001129489
  Entrez Gene 12445 MouseEntrez Gene 25193 RatEntrez Gene 896 Human
  UniProt ID P30281
• Background: CCND3 Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition.
• Synonyms: cyclin D3; D3-type cyclin; G1; OTTHUMP00000016390; S-specific cyclin D3

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Cell cycle, Focal adhesion, Jak-STAT signaling pathway, p53 signaling pathway, Wnt signaling pathway