IL10RA Rabbit Polyclonal Antibody

CAT#: TA325564

Rabbit Polyclonal IL-10R alpha (Tyr496) Antibody (Phospho-specific)

Product Images

Western blot analysis of IL-10R alpha phosphorylation expression in HuvEc whole cell lysates, The lane on the left is treated with the antigen-specific peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against A synthesized peptide derived from human IL-10R alpha around the phosphorylation site of Tyrosine 496
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 63 kDa
• Gene Name: interleukin 10 receptor subunit alpha
• Database Link:
  NP_001549
  Entrez Gene 3587 Human
  UniProt ID Q13651
• Background: The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines.
• Synonyms: CD210; CD210a; CDW210A; HIL-10R; IL-10R1; IL10R

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway