LYN Rabbit Polyclonal Antibody

CAT#: TA325631

Rabbit Polyclonal Lyn (Tyr507) Antibody (Phospho-specific)

Product Images

Western blot analysis of Lyn phosphorylation expression in H2O2 treated K562 whole cell lysates, The lane on the left is treated with the antigen-specific peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000; IHC: 1:50-1:200
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against A synthesized peptide derived from human Lyn around the phosphorylation site of Tyrosine 507
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 53,56 kDa
• Gene Name: LYN proto-oncogene, Src family tyrosine kinase
• Database Link:
  NP_001104567
  Entrez Gene 17096 MouseEntrez Gene 81515 RatEntrez Gene 4067 Human
  UniProt ID P07948
• Background: Lyn a tyrosine kinase of the Src family that plays a role in B cell antigen-receptor signaling.
• Synonyms: JTK8; p53Lyn; p56Lyn

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: B cell receptor signaling pathway, Chemokine signaling pathway, Epithelial cell signaling in Helicobacter pylori infection, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Long-term depression