LKB1 (STK11) Rabbit Polyclonal Antibody

CAT#: TA325910

Rabbit Polyclonal LKB1 Antibody


USD 345.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Applications WB
Recommended Dilution WB: 1:500-1:2000
Reactivities Human, Mouse
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen The antiserum was produced against A synthesized peptide derived from human LKB1
Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration lot specific
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 65 kDa
Gene Name serine/threonine kinase 11
Background ubiquitously expressed kinase of the CAMKL family with a tumor suppressor activity. Phosphorylates AGS3 (activator of G-protein signaling 3) GPR domains, regulating the interaction of GPR-containing proteins with G-proteins. Strongest expression in testis and fetal liver. Mutations in LKB1 lead to the Peutz-Jeghers cancer syndrome.
Synonyms hLKB1; LKB1; PJS
Reference Data
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Adipocytokine signaling pathway, mTOR signaling pathway

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