AHA1 (AHSA1) Mouse Monoclonal Antibody [Clone ID: 4H9-D7]

CAT#: TA326390

Mouse monoclonal Aha1 Antibody

Product Images

Western blot analysis of Aha1 in HeLa cells (1) and recombinant Aha1 (2) using a 1:1000 dilution of the antibody

Specifications

Product Data

• Clone Name: 4H9-D7
• Applications: WB
• Reactivities: Human, Mouse
• Host: Mouse
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Immunogen: Human Aha1, his tagged
• Formulation: PBS pH7.2, 50% glycerol, 0.09% sodium azide
• Concentration: lot specific
• Purification: Protein G Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: activator of Hsp90 ATPase activity 1
• Database Link:
  NP_036243
  Entrez Gene 217737 MouseEntrez Gene 10598 Human
  UniProt ID O95433
• Background: Aha1 is a member of the Hsp90 cochaperone family, and is thought to stimulate Hsp90 ATPase activity by competing with p23 and other co-chaperones for Hsp90 binding . It may affect a step in the endoplasmicreticulum to Golgi trafficking. Aha1 also interacts with HSPCA/Hsp90 and with the cytoplasmic tail of the vesicular stomatistis virus glycoproteins (VSV G) . Aha1 is expressed in numerous tissues, including thebrain, heart, skeletal muscle, and kidney, and at low levels, the liver and placenta. Aha1 might be a potentialtherapeutic strategy to increase sensitivity to HSP inhibitors .
• Synonyms: AHA1; C14orf3; p38
• Note: Detects ~38kDa, can run up to 45kDa on SDS Page. It sees human Aha1, Mouse Aha1 and Mouse Aha2.