AHA1 (AHSA1) Rabbit Polyclonal Antibody

CAT#: TA326466

Rabbit Polyclonal Anti-Aha1 Antibody

Product Images

Western blot analysis of Aha1 in a rat tissue mix using a 1:1000 dilution of the antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Human, Mouse, Rat. Not yet tested on other species
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Mouse Aha1
• Formulation: PBS pH7.4, 50% glycerol, 0.09% sodium azide
• Concentration: lot specific
• Purification: Protein A Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: activator of Hsp90 ATPase activity 1
• Database Link:
  NP_036243
  Entrez Gene 217737 MouseEntrez Gene 681996 RatEntrez Gene 10598 Human
  UniProt ID O95433
• Background: Aha1 is a member of the Hsp90 cochaperone family, and is thought to stimulate Hsp90 ATPase activity by competing with p23 and other co-chaperones for Hsp90 binding . It may affect a step in the endoplasmic reticulum to Golgi trafficking. Aha1 also interacts with HSPCA/Hsp90 and with the cytoplasmic tail of the vesicular stomatistis virus glycoproteins (VSV G) . Aha1 is expressed in numerous tissues, including the brain, heart, skeletal muscle, and kidney, and at low levels, the liver and placenta. Aha1 might be a potential therapeutic strategy to increase sensitivity to HSP inhibitors .
• Synonyms: AHA1; C14orf3; p38
• Note: Detects ~ 38kDa.