Asic1 Mouse Monoclonal Antibody [Clone ID: S271-44]

CAT#: TA326467

Mouse Monoclonal Anti-ASIC1 Antibody

Product Images

WB of rat brain lysate showing detection of ~60 kDa ASIC1 protein using Anti-ASIC1. Lane 1: MW ladder. Lane 2: Anti-ASIC1 (1:100). Lane 3: Anti-ASIC1 (1:250). Lane 4: Anti-ASIC1 (1:500). Lane 5: Anti-ASIC1 (1:1000). Load: 20 ug RB lysate per lane. Block: 5% milk + TBST 1hr at RT. Primary antibody: Mouse Anti-ASIC1 monoclonal antibody incubated for 60 min at RT. Secondary antibody: Goat Anti-Mouse HRP antibody at 1:50 for 60 min at RT. Colour Development: TMB solution for 30 min at RT.

Specifications

Product Data

• Clone Name: S271-44
• Applications: WB
• Reactivities: Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Fusion protein amino acids 460-526 (Cytoplasmic C-terminus) of mouse ASIC1
• Formulation: PBS pH7.4, 50% glycerol, 0.09% sodium azide
• Concentration: lot specific
• Purification: Protein G Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: acid-sensing (proton-gated) ion channel 1
• Database Link:
  NP_033727
  Entrez Gene 79123 RatEntrez Gene 11419 Mouse
  UniProt ID Q6NXK8
• Background: Acid sensing ion channel ASIC1, also designated ACCN2, BNAC2 and ASIC1a, is present in brain as a 4.3-kb transcript with localization to rat dorsal root ganglia. In situ hybridization of rat brain suggests that ASIC1 is most abundant in the main olfactory bulb, cerebral cortex, hippocampal formation, habenula, basolateral amygdaloid nuclei and cerebellum. ASIC1 and H+-gated currents may contribute to the development of fear and anxiety.
• Synonyms: Accn2; AI843610; ASIC; ASIC1a; B530003N02Rik; BNaC2
• Note: Detects ~60kDa