Dlg2 Mouse Monoclonal Antibody [Clone ID: S18-30]

CAT#: TA326525

Mouse Monoclonal Anti-Chapsyn-110 Antibody

Product Images

Western blot analysis of Chapsyn-110 in rat brain membrane lysates using a 1:1000 dilution of the antibody

Specifications

Product Data

• Clone Name: S18-30
• Applications: WB
• Recommended Dilution: WB: 1-10ug/ml, IHC: 0.1-1.0ug/ml, IF: 1.0-10ug/ml
• Reactivities: Human (weak), Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Fusion protein amino acids 1-852 of rat Chapsyn-110
• Formulation: PBS pH7.4, 50% glycerol
• Concentration: lot specific
• Purification: Protein G Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: discs large homolog 2
• Database Link:
  NP_071618
  Entrez Gene 1740 HumanEntrez Gene 23859 MouseEntrez Gene 64053 Rat
  UniProt ID Q63622
• Background: Chapsyn-110, is a part of the membrane-associated putative guanylate kinase (MAGUK) family. It binds directly to the NMDA receptor, and Shaker K+ channel subunits, and is 70-80% identical to PSD-95/SAP90 and SAP97 . It associated tightly with the postsynaptic density I brain, and mediates the clustering of both NMDA recpetors and K+ channels in heterologous cells. The encoded protein forms a heterodimer with PSD-95 that may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins .
• Synonyms: chapsyn-110; DKFZp781D1854; DKFZp781E0954; FLJ37266; MGC131811; OTTHUMP00000165971; PSD-93; PSD93
• Note: Detects ~110kDa. No cross-reactivity against other MAGUK family members, PSD95, SAP97, SAP102, expressed in transfected cells.