Bim (BCL2L11) Rabbit Polyclonal Antibody

CAT#: TA326639

Rabbit Polyclonal Bim EL Antibody

Product Images

Western blot analysis of Bim in K562 cell lysate with Bim EL antibody at (A) 1 and (B) 2 ug/mL.

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  Immunocytochemistry of BIM EL inK562 cells with BIM EL antibody at 2.5 ug/ml.

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  Immunofluorescence of BIM EL in K562 cells with BIM EL antibody at 2.5 ug/ml.

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  Immunocytochemistry of BIM EL inK562 cells with BIM EL antibody at 2.5 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Bim EL antibody was raised against a peptide corresponding to 15 amino acids near the amino terminus of human Bim.
• Formulation: Bim EL Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Bim EL Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 22 kDa; Observed: 24 kDa
• Gene Name: BCL2 like 11
• Database Link:
  NP_996885
  Entrez Gene 12125 MouseEntrez Gene 64547 RatEntrez Gene 10018 Human
  UniProt ID O43521
• Background: Bim EL Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. Bim, also known as Bcl-2-like protein 11, is a pro-apoptotic member of this family and interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. Multiple isoforms of Bim are known to exist, with Bim EL being the longest isoform (1,2).
• Synonyms: BAM; BIM; BOD

Reference Data

• Protein Families: Druggable Genome