CERD4 (DPF3) Rabbit Polyclonal Antibody

CAT#: TA326677

Rabbit Polyclonal DPF3 Antibody

Product Images

Western blot analysis of DPF3 in mouse brain tissue lysate with DPF3 antibody at (A) 1 and (B) 2 ug/ml.

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  Immunohistochemistry of DPF3 in human brain tissue with DPF3 antibody at 5 ug/mL.

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  Immunofluorescence of DPF3 in human brain tissue with DPF3 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: DPF3 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human DPF3
• Formulation: DPF3 antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: DPF3 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 39 kDa; Observed: 50 kDa
• Gene Name: double PHD fingers 3
• Database Link:
  NP_036206
  Entrez Gene 70127 MouseEntrez Gene 8110 Human
  UniProt ID Q92784
• Background: The DPF3 protein, also known as Cerd4, is a member of the d4 gene family of transcription modulators that also includes DPF1/Neud4 and DPF2/Requiem (1). DPF3 has been shown to be a epigenetic key factor for heart and muscle development and can bind to methylated and acetylated lysine residues of histone 3 and 4, suggesting that DPF3 may play a role in recruiting chromatin remodeling complexes to acetylated histones (2). Two isoforms of DPF3, DPF3a and DPF3b, are required as transcriptional co-activators in SWI/SNF complex-dependent activation of the NF-kappaB RelA/p50 heterodimer (3).
• Synonyms: BAF45C; CERD4

Reference Data

• Protein Families: Transcription Factors