67kDa Laminin Receptor (RPSA) Rabbit Polyclonal Antibody

CAT#: TA326691

Rabbit Polyclonal RPSA Antibody

Product Images

Western blot analysis of RPSA in HepG2 cell lysate with RPSA antibody at (A) 1 and (B) 2 ug/ml.

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  Immunohistochemistry of RPSA in mouse liver tissue with RPSA antibody at 5 ug/mL.

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  Immunofluorescence of RPSA in mouse liver tissue with RPSA antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: RPSA antibody was raised against a 17 amino acid peptide near the carboxy terminus of human RPSA.
• Formulation: RPSA antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: RPSA antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 32 kDa; Observed: 38 kDa
• Gene Name: ribosomal protein SA
• Database Link:
  NP_002286
  Entrez Gene 16785 MouseEntrez Gene 3921 Human
  UniProt ID P08865
• Background: The 40S ribosomal protein SA (RPSA) is a high-affinity, non-integrin family, laminin receptor, also known as 67 kDa laminin receptor or 37 kDa laminin receptor precursor (37LRP) (1). Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes and have been implicated in a variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis (2). RPSA is overexpressed in multiple types of cancers and has recently been shown to act as a cancer-specific death receptor (3).
• Synonyms: 1CHD4; 37LRP; 67LR; ICAS; LAMBR; lamR; LAMR1; LBP; LR; LRP; NEM; p40; SA

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Ribosome