GGA2 Rabbit Polyclonal Antibody

CAT#: TA326980

GGA2 Rabbit Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using GGA2 antibody.

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  Immunofluorescence analysis of MCF-7 cell using GGA2 antibody. Blue: DAPI for nuclear staining.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB 1:500 - 1:2000, IHC 1:50- 1:200, IF 1:50- 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human GGA2
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: golgi associated, gamma adaptin ear containing, ARF binding protein 2
• Database Link:
  NP_055859
  Entrez Gene 74105 MouseEntrez Gene 293455 RatEntrez Gene 23062 Human
  UniProt ID Q9UJY4
• Background: This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly. [provided by RefSeq, Jul 2008]
• Synonyms: VEAR

Reference Data

• Protein Pathways: Lysosome