Adenylate Kinase 1 (AK1) Rabbit Polyclonal Antibody

CAT#: TA327004

Rabbit anti-AK1 Polyclonal Antibody

Product Images

Western blot analysis of HEK-293T cell lysate using AK1 antibody.

• 

  Immunohistochemistry of paraffin-embedded rat spleen using AK1 antibody at dilution of 1:200 (400x lens).

• 

  Immunohistochemistry of paraffin-embedded human thyroid cancer using AK1 antibody at dilution of 1:200 (400x lens).

• 

  Immunofluorescence analysis of A549 cell using AK1 antibody. Blue: DAPI for nuclear staining.

Specifications

Product Data

• Applications: ICC/IF, IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50- 1:200;IF 1:50- 1:200
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human AK1
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: adenylate kinase 1
• Database Link:
  NP_000467
  Entrez Gene 11636 MouseEntrez Gene 203 Human
  UniProt ID P00568
• Background: Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.
• Synonyms: HTL-S-58j

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Purine metabolism