Ataxin 3 (ATXN3) Rabbit Polyclonal Antibody

CAT#: TA327022

ATXN3 Rabbit Polyclonal Antibody

Product Images

Western blot analysis of MCF-7 cell lysate using ATXN3 antibody.

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  Immunohistochemistry of paraffin-embedded human lung cancer using ATXN3 antibody at dilution of 1:200 (400x lens).

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  Immunohistochemistry of paraffin-embedded rat kidney using ATXN3 antibody at dilution of 1:200 (400x lens).

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  Immunofluorescence analysis of HeLa cell using ATXN3 antibody. Blue: DAPI for nuclear staining.

Specifications

Product Data

• Applications: ICC/IF, IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50- 1:200;IF 1:50- 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human ATXN3
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: ataxin 3
• Database Link:
  NP_004984
  Entrez Gene 60331 RatEntrez Gene 110616 MouseEntrez Gene 4287 Human
  UniProt ID P54252
• Background: Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Sep 2009]
• Synonyms: AT3; ATX3; JOS; MJD; MJD1; SCA3

Reference Data

• Protein Families: Druggable Genome, Transcription Factors