ABO Rabbit Polyclonal Antibody

CAT#: TA327092

ABO Rabbit Polyclonal Antibody

Product Images

Western blot analysis of extracts of K562 cell lines, using ABO antibody.

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  Immunofluorescence analysis of MCF7 cell using ABO antibody. Blue: DAPI for nuclear staining.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB 1:500 - 1:2000, IHC 1:50- 1:200, IF 1:50- 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human ABO
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
• Database Link:
  NP_065202
  Entrez Gene 80908 MouseEntrez Gene 100301568 RatEntrez Gene 28 Human
  UniProt ID P16442
• Background: This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The O blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene. [provided by RefSeq, Jul 2008]
• Synonyms: A3GALNT; A3GALT1; GTB; NAGAT

Reference Data

• Protein Families: Secreted Protein, Transmembrane
• Protein Pathways: Glycosphingolipid biosynthesis - lacto and neolacto series, Metabolic pathways