CSNK2A2 Rabbit Polyclonal Antibody

CAT#: TA327103

Rabbit anti-CSNK2A2 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using CSNK2A2 antibody.

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  Immunohistochemistry of paraffin-embedded rat lung using CSNK2A2 antibody at dilution of 1:100 (400x lens).

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  Immunohistochemistry of paraffin-embedded human lung cancer using CSNK2A2 antibody at dilution of 1:100 (400x lens).

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  Immunohistochemistry of paraffin-embedded human liver cancer using CSNK2A2 antibody at dilution of 1:100 (400x lens).

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  Immunohistochemistry of paraffin-embedded mouse lung using CSNK2A2 antibody at dilution of 1:100 (400x lens).

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50 - 1:200;IF 1:50 - 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human CSNK2A2
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 41 kDa
• Gene Name: casein kinase 2 alpha 2
• Database Link:
  NP_001887
  Entrez Gene 13000 MouseEntrez Gene 307641 RatEntrez Gene 1459 Human
  UniProt ID P19784
• Background: Casein kinase I (also designated CKI) and casein kinase II (CKII) compose a family of serine/threonine protein kinases which are present in all eukaryotes examined to date. Casein kinase I family members, which include casein kinase Iå, I©, I∂ and Ie, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an å2¡Ò2 or an åå¡Ò2 structure. The a catalytic subunit is stimulated by the ¡Ò regulatory subunit, which undergoes autophosphorylation. Casein kinase II activity is high in the cytosol and nucleus of proliferating and differentiating cells. Casein kinase II is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.
• Synonyms: CK2A2; CK2alpha; CK2alpha'; CSNK2A1

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Adherens junction, Tight junction, Wnt signaling pathway