XPA Rabbit Polyclonal Antibody

CAT#: TA327111

XPA Rabbit Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using XPA antibody.

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  Immunohistochemistry of paraffin-embedded human lung cancer using XPA antibody at dilution of 1:200 (200x lens).

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  Immunohistochemistry of paraffin-embedded rat brain using XPA antibody at dilution of 1:200 (200x lens).

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50 - 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human XPA
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 31 kDa
• Gene Name: XPA, DNA damage recognition and repair factor
• Database Link:
  NP_000371
  Entrez Gene 22590 MouseEntrez Gene 298074 RatEntrez Gene 7507 Human
  UniProt ID P23025
• Background: This gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]
• Synonyms: XP1; XPAC

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Nucleotide excision repair