ETV6 Rabbit Polyclonal Antibody

CAT#: TA327117

Rabbit anti-ETV6 Polyclonal Antibody

Product Images

Western blot analysis of extracts of A431 cell lines, using ETV6 antibody.

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  Immunohistochemistry of paraffin-embedded human lung cancer using ETV6 antibody at dilution of 1:200 (400x lens).

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  Immunohistochemistry of paraffin-embedded human lung using ETV6 antibody at dilution of 1:200 (400x lens).

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  Immunohistochemistry of paraffin-embedded human esophagus using ETV6 antibody at dilution of 1:200 (400x lens).

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50- 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human ETV6
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: ETS variant 6
• Database Link:
  NP_001978
  Entrez Gene 14011 MouseEntrez Gene 312777 RatEntrez Gene 2120 Human
  UniProt ID P41212
• Background: This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.
• Synonyms: ABL; TEL; THC5

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Dorso-ventral axis formation